HIGHLY EFFICIENT CLINICAL TRIALS SIMULATOR (HECT): SOFTWARE APPLICATION FOR PLANNING AND SIMULATING PLATFORM ADAPTIVE TRIALS [VERSION 2; PEER REVIEW: 1 APPROVED, 2 APPROVED WITH RESERVATIONS]

Highly Efficient Clinical Trials Simulator (HECT): Software application for planning and simulating platform adaptive trials [version 2; peer review: 1 approved, 2 approved with reservations]

Background: Adaptive designs and platform designs are among two common clinical trial innovations that are increasingly being used to manage medical intervention portfolios and attain faster regulatory dabcaps approvals.Planning of adaptive and platform trials necessitate simulations to understand how a set of adaptation rules will likely affect th

read more



Emotional Egocentricity Bias across the life-span

In our daily lives, we often have to quickly estimate the emotions of our conspecifics in order to have successful social interactions.While this estimation process seems quite easy when we are ourselves in a neutral or equivalent emotional state, it has recently been shown that in case of incongruent emotional states between ourselves and the othe

read more